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Apoptosis
Researchers' work adds to apoptosis body of knowledge
April 21st, 2006
Apoptosis data are the focus of recent research from the United States and Italy. Study 1: Recent research from the United States has reported that phorbol ester-induced apoptosis in prostate cancer cells involves protein kinase C (PKC) delta. "It is well established that activation of PKC by phorbol esters promotes apoptosis in androgen-dependent prostate cancer cells. However, there is limited information regarding the cellular mechanisms involved in this effect," wrote A.M. Gonzalez-Guerrico and colleagues, University of Pennsylvania. "In this report we identified a novel autocrine pro-apoptotic loop triggered by PKCdelta...
Source: Science Letter (2006-04-21)
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