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Biological Chemistry



Scientists discover novel way to remove iron from ferritin



November 20th, 2007

Oakland, CA -- A new study led by Children's Hospital Oakland Research Institute senior scientist, Elizabeth Theil, Ph.D., is the first to suggest that a small protein or heptapeptide (seven amino acids wrapped into one unit) could be used to accelerate the removal of iron from ferritin. The results of this study may help scientists develop new medications that dramatically improve the removal of excess iron in patients diagnosed with blood diseases such as B-Thalassemia (Cooley's anemia) or Sickle Cell Disease.

The study appears in this month's issue of the Journal of Biological Chemistry and was conducted by Dr. Theil and her co-authors Xiaofeng S. Liu, postdoctoral...


Source: Science Letter (2007-11-20)

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