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Bioscience
Powerful integration of lipid metabolic profiling with gene expression analysis
November 20th, 2007
A recently published research article in the "Journal of Proteome Research", authored by researchers from the Nestlé Reserarch Center, Genomatix Software GmbH, Rosetta Inpharmatics LLC, CXR Biosciences Ltd, the Cancer Research UK Molecular Pharmacology Unit demonstrates the synergisms and enhanced analytic power of the combination of thorough metabolic profiling with the unique and proprietary microarray analysis methods of Genomatix Software GmbH. The study elucidated the effects on Mouse lipid metabolism by the disruption of hepatic Cytochrome P450 reductase (POR) in a POR deficient knock-out mouse model. It clearly could demonstrate that though gene expression and lipid metabolism in...
Source: Science Letter (2007-11-20)
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