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Hypertension
OHSU researchers identify master switch that regulates blood pressure
November 20th, 2007
A team of Oregon Health & Science University researchers studying a rare form of hypertension has identified the mechanism by which they believe a protein complex in the kidney operates as a master switch that regulates blood pressure, a finding that has broad implications for the treatment of more common forms of hypertension. The team led by David H. Ellison, M.D. – whose findings are described in a paper being published (NOV. 1) in the Journal of Clinical Investigation – likens the switch to a rheostat that modulates the balance of salt and potassium in the kidney, thereby raising or lowering blood pressure. When the switch malfunctions, the group suggests, high blood pressure or...
Source: Science Letter (2007-11-20)
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