Stem Cell Research

Skeletal muscle progenitor cells are bone marrow derived with different fates

Published in Stem Cell Week, March 3rd, 2003

"Vascular progenitors were previously isolated from blood and bone marrow; herein, we define the presence, phenotype, potential, and origin of vascular progenitors resident within adult skeletal muscle," researchers in the United States reported.

"Two distinct populations of cells were simultaneously isolated from hindlimb muscle: the side population (SP) of highly purified hematopoietic stem cells and non-SP cells, which do not reconstitute blood. Muscle SP cells were found to be derived from, and replenished by, bone marrow SP cells; however, within the muscle environment, they were phenotypically distinct from marrow SP cells," said S.M. Majka and colleagues,...

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Source: Stem Cell Week (2003-03-03)

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