Lymphoid Development
Frizzled 9 knock-out mice have abnormal B-cell development
Published in Stem Cell Week, May 23rd, 2005
According to a recently published report from the United States, "The binding of frizzled (Fzd) receptors by their Writ ligands results in the inhibition of beta-catenin degradation and subsequent transcription of beta-catenin/LEF-inducible genes.
"The beta-catenin pathway is known to be involved in development, tumorigenesis, and stem cell self-renewal. In humans, the FZD9 gene lies in the region of chromosome 7q11.23 deleted in the neurodevelopmental disorder, Williams-Beuren syndrome (WBS)."
"Fzd9-/- mice show no obvious features of WBS, but reveal a role for Fzd9 in...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Stem Cell Week
Source: Stem Cell Week (2005-05-23)
More Articles from Stem Cell Week
- Fetal Hematopoiesis
Placenta is a niche for hematopoietic stem cells - Multiple Sclerosis
HSCT induces long-lasting suppression of inflammation in multiple sclerosis - Neural Stem Cell Research
PACAP promotes differentiation of neural stem cells into astrocytes - Neural Stem Cell Research
Tumor cells attract endogenous precursor cells whose presence is antitumorigenic - Stem Cell Research
Multipotent cells isolated from human term placenta - Angiology
Cell growth stimulants hasten new vessel growth in ischemic hindlimbs - More from this issue of Stem Cell Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
