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Cancer Immunotherapy
Cancers could be treated by targeting endothelial-cell growth factor-1
August 14th, 2006
Cancers could be treated by targeting endothelial-cell growth factor-1 (ECGF1). According to recent research published in the journal Blood, "Characterization of the antigens recognized by tumor-reactive T cells isolated from patients successfully treated with allogeneic HLA-matched hematopoietic stem cell transplantation (SCT) can lead to the identification of clinically relevant target molecules. We isolated tumor-reactive cytotoxic CD8+ T-cell (CTL) clones from a patient successfully treated with donor lymphocyte infusion for relapsed multiple myeloma after allogeneic HLA-matched SCT." "Using cDNA expression cloning, the target molecule of...
Source: Stem Cell Week (2006-08-14)
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