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Graft-versus-Host Disease
Endothelial cell-derived microparticles elevated in acute graft-versus-host disease
August 14th, 2006
Endothelial cell-derived microparticle levels are elevated in acute graft-versus-host disease in allogeneic hematopoietic stem cell recipients. According to a study from Germany, "Alterations of microparticles derived from different cell types are described in a number of diseases associated with inflammation and hemostatic disorders. In this prospective study, we firstly analyzed endothelial cell derived microparticles (EMP) in 19 hematopoietic stem cell recipients. "Cultured human umbilical vein endothelial cells (HUVEC) stimulated with tumor necrosis factor-alpha (TNF-alpha) served as positive controls. EMP were analyzed by fluorescent activated...
Source: Stem Cell Week (2006-08-14)
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