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Hair Development
miRNA-processing enzyme dicer essential for hair follicle morphogenesis and maintenance
August 14th, 2006
The microRNA-processing enzyme dicer is essential for hair follicle morphogenesis and maintenance. According to recent research published in the journal Current Biology, "The discovery that microRNAs (miRNAs) play important roles in regulating gene expression via post-transcriptional repression has revealed a previously unsuspected mechanism controlling development and progenitor-cell function; however, little is known of miRNA functions in mammalian organogenesis. Processing of miRNAs, and their assembly into the RNA-induced silencing (RISC) complex requires the essential multifunctional enzyme Dicer." "We found that Dicer mRNA and multiple...
Source: Stem Cell Week (2006-08-14)
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