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Embryonic Stem Cell Research
Embryonic stem cells generate insulin-secreting cells
August 14th, 2006
Insulin-secreting cells have been generated from embryonic stem cells. According to a study from Iran, "A growth factor-mediated selection method was used to obtained insulin-secreting cells from human embryonic stem cells (hESC; Royan H1). "Our resultant cells were positive for dithizone, a zinc-chelating agent known to selectively stain pancreatic beta cells and immunoreactive for antibodies against insulin, glucagon, and C-peptide." "Semiquantitative reverse transcription-polymerase chain reaction detected expression of proinsulin, insulin and other pancreatic beta-cell-related genes, such as Nkx6.1, Is11, Glut2, Pax4, and...
Source: Stem Cell Week (2006-08-14)
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