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Neurogenesis
Neurogenesis lacking in adult cerebellum after Purkinje cell degeneration
August 14th, 2006
Neurogenesis is lacking in the adult cerebellum after Purkinje cell degeneration and growth factor infusion. "Although constitutive neurogenesis exclusively occurs in restricted regions of the adult mammalian brain, resident progenitors can be isolated from many different CNS sites, and neuronal neogeneration can be stimulated in vivo by injury or infusion of growth factors. "To ask whether latent compensatory mechanisms, which may be exploited to promote repair processes, are present throughout the CNS, we examined the neurogenic potentialities of the adult rat cerebellum in normal conditions, following injury, and after infusion of growth factors,"...
Source: Stem Cell Week (2006-08-14)
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