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Stem Cell Research
Cardiac myxoma cells exhibit embryonic endocardial stem cell features
August 14th, 2006
Cardiac myxoma cells exhibit embryonic endocardial stem cell features. "The origin of myxoma, the most frequent tumor of the heart, remains uncertain. Previous phenotypic characterizations have shown heterogeneous results and the most recent hypothesis suggests that cardiac myxoma originates from a primitive pluripotential cardiogenic cell," researchers in Italy report. According to A. Orlandi and colleagues at the University of Roma Tor Vergata, "We investigated the expression of actin isoforms in 30 left atrial myxomas by immunohistochemistry and in eight consecutive tumours by RT-PCR. "alpha-Smooth muscle actin (alpha-SMA)...
Source: Stem Cell Week (2006-08-14)
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