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Stem Cell Research
Stem cell factor fused with erythropoietin mimetic peptide expressed in Escherichia coli
August 14th, 2006
Recent research from the People's Republic of China has documented the high-level expression of human stem cell factor (SCF) fused with erythropoietin mimetic peptide (EMP) in Escherichia coli. "SCF and erythropoietin are essential for normal erythropoiesis and induce proliferation and differentiation synergistically for erythroid progenitor cells. Here, we report our work on construction of SCF/EMP fusion protein gene, in which human SCIF cDNA (1-165aa) and EMP sequence (20aa) were connected using a short (GGGGS) or long (GGGGSGGGGGS) linker sequence," wrote L. Su and colleagues, Chinese Academy of Medical Science. "The SCF/EMP gene was...
Source: Stem Cell Week (2006-08-14)
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