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Stem Cell Research
Neurosphere-derived neurons similar to immature neurons differentiating in vivo
August 14th, 2006
Neurosphere-derived neurons are similar to immature neurons differentiating in vivo. "Neural stem cells can be propagated in culture as neurospheres, yielding neurons and glial cells upon differentiation. Although the neurosphere model is widely used, the functional properties of the neurosphere-derived neurons have been only partially characterized, and it is unclear whether repeated passaging alters their functional properties," scientists in Italy report. According to F. Pagani and colleagues at the University of Roma La Sapienza, "In this study, we analyzed voltage- and transmitter-gated responses in neuron-like cells obtained by differentiating...
Source: Stem Cell Week (2006-08-14)
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