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Stem Cell Transplantation
Adoptive T-cell transfer may protect from adenovirus-related complications
August 14th, 2006
Adoptive virus-specific T-cell transfer may protect from adenovirus-related complications following stem cell transplantation. According to a recently published study from Germany, "During periods of immunosuppression, such as postallogeneic stem cell transplantation (SCT), patients are at significant risk for severe viral infections. Human adenovirus (HAdV) infection is a serious complication post-SCT, especially in children. "Virus-specific T cells are essential for the clearance of HAdV, as antiviral chemotherapy has revealed limited success. We present feasibility data for a new treatment option using virus-specific donor T cells for adoptive...
Source: Stem Cell Week (2006-08-14)
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