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Tissue Engineering
3-D scaffold plus nonviral gene carrier enhances mesenchymal stem cell DNA expression
August 14th, 2006
A 3-dimensional tissue engineered scaffold plus a nonviral gene carrier enhances mesenchymal stem cell DNA expression. "The objective of this study is to enhance the expression of a plasmid DNA for mesenchymal stem cells (MSC) by combination of 3-dimensional (3D) tissue engineered scaffolds and nonviral gene carrier. "As a carrier of plasmid DNA, dextran-spermine cationic polysaccharide was prepared by means of reductive-amination between oxidized dextran and the natural oligoamine, spermine," scientists writing in the journal Biomaterials report. According to the authors, "As the MSC scaffold, collagen sponges reinforced...
Source: Stem Cell Week (2006-08-14)
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