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Stem Cell Research
Tmtsp is a marker gene for primitive hematopoietic cells and endothelial cells
August 14th, 2006
Transmembrane molecule with thrombospondin module has been identified as a marker gene for primitive hematopoietic cells and endothelial cells. "Using an in silico database search, we identified a novel gene encoding a cell surface molecule with a thrombospondin domain, and designated the gene as transmembrane molecule with thrombospondin module (Tmtsp). "Expression profiling of Tmtsp using specific monoclonal antibodies and Venus, a variant of yellow fluorescent protein knock-in mice in the Tmtsp locus, demonstrated its specific expression in hematopoietic and endothelial cells," investigators in Japan report. According to S.I....
Source: Stem Cell Week (2006-08-14)
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