Stem Cell Research
Studies from University of Tokyo, Institute of Medical Science in the area of stem cell research published
Published in Stem Cell Week, January 22nd, 2007
Investigators publish new data in the report "Overexpression of interleukin 21 induces expansion of hematopoietic progenitor cells. The interleukin 21 (IL-21) receptor is expressed on T-cells, B-cells, and natural killer cells, and IL-21 is critical for regulating immunoglobulin production in vivo in cooperation with IL-4. So far, however, little is known about a role for IL-21 outside the immune system," scientists in Tokyo, Japan report.
"We investigated the effect of IL-21 on hematopoiesis in vivo by using the hydrodynamics gene-delivery method. Overexpression of IL-21 increases Sca-1+ cells in the periphery and spleen. It also increases the numbers of c-Kit+,...
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Source: Stem Cell Week (2007-01-22)
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