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Stem Cell Research

New stem cell research study findings have been reported by researchers at National Institutes of Health

Published in Stem Cell Week, November 19th, 2007

According to a study from the United States, "We have previously described pluripotent, parity-induced mammary epithelial cells (PI-MEC) marked by Rosa26-lacZ expression in the mammary glands of parous females, PI-MEC act as lobule-limited epithelial stem/progenitor cells. To determine whether parity is necessary to generate PI-MEC, we incubated mammary explant cultures from virgin mice in vitro with insulin alone (1), hydrocortisone alone (H), prolactin alone (Prl), or a combination of these lactogenic hormones (IHPrl)."

"Insulin alone activated the WAP-Cre gene. Hydrocortisone and prolactin alone did not. Any combination of hormones that included insulin was...

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