Hyperplasia
New hyperplasia research reported from University of Cincinnati, Department of Ophthalmology
Published in Stem Cell Week, April 14th, 2008
A report, 'Excess FGF-7 in corneal epithelium causes corneal intraepithelial neoplasia in young mice and epithelium hyperplasia in adult mice,' is newly published data in American Journal of Pathology. According to a study from the United States, "We hypothesized that human ocular surface squamous neoplasia (OSSN) may result from the continuous growth stimulation of corneal epithelial progenitor cells. In the present study, we analyzed the effects of excess fibroblast growth factor-7 (FGF-7) on both the proliferation and differentiation of corneal epithelium in a novel Krt12-rtTA/tet-O-FGF-7 double transgenic mouse model in which cornea-specific FGF-7 overexpression is achieved by...
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Source: Stem Cell Week (2008-04-14)
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