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Stem Cell Week

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Dermatofibrosarcoma



Research conducted at Saga University, Medical Department has provided new information about dermatofibrosarcoma



August 25th, 2008

According to recent research published in the Journal of Dermatology, "Making a differential diagnosis to distinguish dermatofibrosarcoma protuberans (DFSP) from dermatofibroma (DF) is occasionally difficult. In those instances, CD34 and factor XIIIa have been used as valuable differential markers."

"The histogenesis of DFSP, however, remains uncertain and controversial, although it is generally thought to be a neuromesenchymal neoplasm. Nestin is an intermediate filament protein that was first observed in neuroectodermal stem cells. We investigated the expression of nestin in order to distinguish between DFSP and DF in combination with the use of conventional...


Source: Stem Cell Week (2008-08-25)

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