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Stem Cell Week

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Hepatitis B Virus



Researchers at Nanjing Medical University publish new data on hepatitis B virus



August 25th, 2008

According to recent research published in the Journal of Viral Hepatitis, "We have previously showed that endothelial progenitor cells (EPCs) through uptake of hepatitis B virus (HBV) may play a critical role in mediating extrahepatic HBV diseases. However, it remains to be elucidated whether mesenchymal stem cells (MSCs) are capable of mediating HBV trans-infection into extrahepatic tissues."

"In this study, we showed that HBV antigens, HBV DNA and the viral particles were detected in MSCs after 3 days virus challenge. Neither HBV covalently closed circular DNA nor pregenomic RNA were detected in MSCs. Intravenously transplantation of HBV-exposed MSCs into...


Source: Stem Cell Week (2008-08-25)

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