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Ischemia
New ischemia findings from L.A. Mylotte and co-researchers published
August 25th, 2008
According to a study from Galway, Ireland, "The application of mesenchyrnal stem cells (MSCs) for myocardial repair following ischemic injury is of strong interest, but current knowledge regarding the survival and retention of differentiation potency of stem cells under ischemic conditions is limited. The present study investigated the effects of ischemia and its components (hypoxia and glucose depletion) on MSC viability and multipotency." "We demonstrate that MSCs have a profoundly greater capacity to survive under conditions of ischemia compared with cardiomyocytes, measured by detecting changes in cellular morphology, caspase activity and phosphatidylserine...
Source: Stem Cell Week (2008-08-25)
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