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Lichen Sclerosus
Data from Queen Mary Hospital advance knowledge in lichen sclerosus
August 25th, 2008
"Graft-versus-host disease (GVHD) often complicates allogeneic stem cell transplantation (SCT) and affects mainly the gut, liver, lung and skin. The microscopic morphological features of late-phase sclerodermatous chronic GVHD in the skin, namely epidermal atrophy, lymphoplasmacytic infiltration, dense dermal fibrosis and adnexal atrophy, are histologically indistinguishable from those in sporadic systemic sclerosis, morphoea and the related condition of lichen sclerosus," scientists writing in the British Journal of Dermatology report. "Mucosal orifices including those of the genitourinary system may be severely affected. We present three SCT recipients with...
Source: Stem Cell Week (2008-08-25)
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