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Stem Cell Week

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Pancreatitis



Data on pancreatitis published by researchers at Columbia University



August 25th, 2008

"Chronic pancreatitis is a known risk factor for pancreatic adenocarcinoma. Recent work has pointed to a role for bone marrow-derived progenitor cells (BMDCs) in chronic inflammation-based carcinogenesis," researchers in the United States report.

"Consequently, the role of BMDCs in chronic pancreatitis was investigated. The fate of BMDCs was followed using green fluorescent protein and the Y chromosome as bone marrow markers in gender-mismatched transplanted mice treated with repeated injections of cerulein for up to 45 weeks. The phenotype of engrafted BMDCs was assessed based on the co-expression of bone marrow and pancreatic markers. After 45 weeks of cerulein...


Source: Stem Cell Week (2008-08-25)

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