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Penile Induration
New findings from University of California in the area of penile induration described
August 25th, 2008
"The primary histologic finding in many urologic disorders, including Peyronie's disease (PD), is fibrosis, mainly mediated by the transforming growth factor beta 1 (TGF beta 1). To determine whether another member of the TGF beta family, myostatin, (1) is expressed in the human PD plaque and normal tunica albuginea (TA), their cell cultures, and the TGF beta 1-induced PD lesion in the rat model; (ii) is responsible for rnyofibroblast generation, collagen deposition, and plaque formation; and (iii) mediates the profibrotic effects of TGF beta 1 in PD," scientists writing in the Journal of Sexual Medicine report. "Human TA and PD tissue sections, and cell cultures...
Source: Stem Cell Week (2008-08-25)
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