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Stem Cell Research
Findings from S. Agarwal and co-authors provide new insights into stem cell research
August 25th, 2008
"Differentiation of human embryonic stem cells (hESCs) to specific functional cell types can be achieved using methods that mimic in vivo embryonic developmental programs. Current protocols for generating hepatocytes from hESCs are hampered by inefficient differentiation procedures that lead to low yields and large cellular heterogeneity," scientists writing in the journal Stem Cells report. "We report here a robust and highly efficient process for the generation of high-purity (70%) hepatocyte cultures from hESCs that parallels sequential hepatic development in vivo. Highly enriched populations of definitive endoderm were generated from hESCs and then induced to...
Source: Stem Cell Week (2008-08-25)
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