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Graft-Versus-Host Disease

Studies from University of Barcelona provide new data on graft-versus-host disease

Published in Stem Cell Week, November 3rd, 2008

According to recent research from Barcelona, Spain, "Chronic graft-vs-host disease (GVHD) remains the most common late complication of allogeneic hematopoietic stem cell transplantation (HSCT), despite improvements in its prophylaxis. Although the graft-vs-leukemia effect associated with the development of chronic GVHD may be beneficial in controlling the underlying disease, patients with chronic GVHD are prone to fatal infections owing to multiple abnormalities of their reconstructed immune systems."

"Infection is the most common cause of death in patients with chronic GVHD. Chronic GHVD may also compromise a patient's quality of life as a result of long-term...

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