World Journal of Gastroenterology
Are bone marrow mononuclear cells effective in reducing hepatic lesions?
Published in Stem Cell Week, November 3rd, 2008
Liver fibrosis occurs in the setting of chronic injury caused by different etiologies constituting a serious worldwide public health problem. In addition to schistosomiasis, hepatopathies due to alcohol, viral hepatitis, drugs, metabolic and autoimmune diseases, and congenital abnormalities are important causes of liver fibrosis. New therapeutic strategies aiming to minimize damages caused by hepatic fibrogenesis in chronic liver diseases are of great interest. Adult bone marrow contains pluripotent stem cells with the ability to differentiate into diverse cell types, including hepatocytes. The regenerative potential of bone marrow stem cells has been tested in experimental models of...
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Source: Stem Cell Week (2008-11-03)
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