Hydrocephalus
New hydrocephalus study findings have been reported from University of Manchester
Published in Stem Cell Week, June 8th, 2009
"Fetal-onset hydrocephalus (HQ, which affects between 1:500 and 1:5000 live human births, results from unequal production and drainage of cerebrospinal fluid (CSF) and is associated with abnormal development of the cerebral cortex leading to severe neurological deficits. We previously found that in the hydrocephalic Texas rat, the CSF of affected fetuses induced a cell cycle arrest in neural progenitor cells," scientists in Manchester, the United Kingdom report.
"Here, we show that alterations in folate metabolism in the CSF of the developing cerebrum are likely responsible for this effect. We identified 3 folate enzymes in the CSF and demonstrate that low levels of one...
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Source: Stem Cell Week (2009-06-08)
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