Thrombosis

Findings from D.J. Lee and co-researchers advance knowledge in thrombosis

Published in Stem Cell Week, June 8th, 2009

According to recent research published in the journal Tissue Engineering Part a, "Although calcification remains as the main clinical concern associated with bioprosthetic heart valve replacement surgery, there is evidence that tissue deterioration leads to thromboembolism. In such instances, measures that prevent thrombosis may be beneficial."

"To minimize thrombosis, endothelialization of the valve surface before implantation has been proposed to facilitate coverage. In this study we aimed to define the optimal flow parameters for the endothelialization of decellularized heart valves using endothelial progenitor cell (EPC)-derived endothelial cells (ECs). We...

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Source: Stem Cell Week (2009-06-08)

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