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Graft-Versus-Host Disease
Study findings on graft-versus-host disease are outlined in reports from Leiden University
June 15th, 2009
"Recent evidence indicates that bone marrow-derived cells contribute to endothelial and epithelial cell renewal in recipients of an allogeneic stem-cell transplantation (SCT). Controversy remains on the biological significance of these donor-derived cells," researchers in Netherlands report. "This study investigated the occurrence of endothelial and epithelial cell chimerism in relation to the conditioning regimen, time interval after SCT, and development of acute and chronic graft-versus-host disease (GVHD). Fifty-five skin biopsy samples from 35 female patients transplanted with a male donor were screened for donor-derived endothelial and epithelial cells using in...
Source: Stem Cell Week (2009-06-15)
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