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University of California - San Diego

Researchers identify protein needed to develop auditory neurons

Published in Stem Cell Week, January 25th, 2010

Loss of spiral ganglion neurons or hair cells in the inner ear is the leading cause of congenital and acquired hearing impairment. Researchers at the University of California, San Diego, School of Medicine and the National Institutes of Health found that Sox2, a protein that regulates stem cell formation, is involved in spiral ganglion neuron development. The study was published in the January 13 issue of the Journal of Neuroscience.

"These findings may provide the first step toward regenerating spiral ganglion neurons, the nerve cells that send sound representations to the brain," said Alain Dabdoub, PhD, co-investigator and assistant professor of surgery with the...

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