N.N. Burdenko Neurosurgical Institute, Moscow
Prognostic relevance of molecular alterations in glioblastomas evaluated
Published in Surgery Litigation and Law Weekly, October 7th, 2005
"In patients with glioblastoma, age <50 years was identified as a consistent prognostic variable. In addition, the prognosis for these patients may be determined by a complex interaction between age and genetic alterations," researchers in Russia reported.
"The objective of the current study was the molecular analysis of glioblastomas from adult patients age <50 years ('young adults'). The authors analyzed a set of 189 glioblastoma specimens. Fluorescence in situ hybridization was performed with a set of 10 chromosome probes (1p36, 1q25, centromere probe 7 [CEP7],...
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