Technical University of Munich
Esophageal squamous cell carcinoma predicted MTR A2756G polymorphism
Published in Surgery Litigation and Law Weekly, April 14th, 2006
According to a study from Germany, "The present study retrospectively examined the correlation between the outcome of patients with locally advanced oesophageal squamous cell carcinoma (cT3-4 cN0-1 cM0) after multimodal treatment (radiochemotherapy±surgical resection), and the presence of genetic polymorphisms in genes involved in folate metabolism. In total, 68 patients who took part in a prospective multicentric trial received 5-fluorouracil (FU)-based radiochemotherapy, optionally followed by surgery."
"DNA was extracted from pretherapeutic tumor biopsies...
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