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M.D. Anderson Cancer Center

Choice of chemotherapy for liver metastasis may impact surgical outcomes

Published in Surgery Litigation and Law Weekly, May 26th, 2006

Patients and their physicians should be careful when selecting a chemotherapy drug to treat colorectal cancer that has spread to the liver, say researchers at The University of Texas M. D. Anderson Cancer Center in Houston, particularly if they are candidates for surgery.

While surgery to remove liver metastases also has proven beneficial, both of the most commonly used chemotherapy drugs to treat these tumors can seriously injure the liver, the researchers report in a recent issue of the Journal of Clinical Oncology. Furthermore the damage caused to the liver by these preoperative chemotherapy regimens can adversely affects long-term surgical outcomes.

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