Biomedical Engineering

Recent studies from Jewish Hospital, Department of Orthopaedic Surgery add new data to biomedical engineering

Published in Surgery Litigation and Law Weekly, December 8th, 2006

Data detailed in "Medial collateral ligament healing in macrophage metalloelastase (MMP-12)-deficient mice" have been presented. According to recent research from the United States, "Medial collateral ligament (MCL) injuries heal by a wound repair scar response controlled by a complex cellular and cytokine environment. Many enzymes participate in wound repair, particularly the matrix metalloproteinases."

"We hypothesize macrophage metalloelastase (MME/MMP-12) deficiency results in impaired healing of MCL injury. One hundred fifty MME-deficient and 150 WT (MME+/+) mice underwent knee MCL transection with the opposite knee as a sham operated control. Mice were sacrificed...

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Source: Surgery Litigation and Law Weekly (2006-12-08)

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