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Proteomics

Data on proteomics detailed by researchers at University Hospital

Published in Surgery Litigation and Law Weekly, February 9th, 2007

Research findings, "Carcinoma-associated eIF3i overexpression facilitates mTOR-dependent growth transformation," are discussed in a new report. According to recent research from Germany, "Molecular processes controlling mRNA translation are complex, multilayered, and their deregulation can lead to cancer pathogenesis. Eukaryotic initiation factor 3 (eIF3) is involved in the initiation process of protein translation and overexpression of its subunit eukaryotic translation initiation factor i (eIF3i) has been observed in carcinomas."

"Nevertheless, the potential role of eIF3i in carcinogenesis is poorly understood. Here, we show that in vitro overexpression of human eIF3i...

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