Acute Myeloid Leukemia Therapy
Scientists at University College, Department of Haematology describe research in acute myeloid leukemia therapy
Published in Surgery Litigation and Law Weekly, February 23rd, 2007
Research findings, "Continuous delivery of human type I interferons (alpha/beta) has significant activity against acute myeloid leukemia cells in vitro and in a xenograft model," are discussed in a new report. "In this study, we focused primarily on the antileukemic activity of interferon-beta (IFN-beta) in a murine xenograft model of acute myeloid leukemia (AML). Bolus administration of recombinant IFN-beta via the subcutaneous or intravenous route failed to show efficacy in mice injected with AML cells despite achieving peak plasma IFN-beta levels of more than 200 IU/mL," investigators in the United States report.
"In contrast, stable expression of IFN-beta following...
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