Published in Surgery Litigation and Law Weekly, July 13th, 2007
Study 1: Investigators publish new data in the report "Regulation of antioxidants and phase 2 enzymes by shear-induced reactive oxygen species in endothelial cells. Exposure of vascular endothelial cells (ECs) to steady laminar shear stress activates the NF-E2-related factor 2 (Nrf2) which binds to the antioxidant response element (ARE) and upregulates the expression of several genes. The onset of shear is known to increase the EC reactive oxygen species (ROS) production, and oxidative stress can activate the ARE," investigators in the United States report.
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