Breast Cancer Therapy
Reports from Wayne State University highlight recent research in breast cancer therapy
Published in Surgery Litigation and Law Weekly, August 17th, 2007
Researchers detail in "Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu," new data in breast cancer. According to a study from the United States, "The HER2/neu oncogene is an important diagnostic and prognostic factor and therapeutic target in breast and other cancers. We developed and characterized a breast cancer cell line (Bam1a) that overexpresses the activated HER2/neu and ErbB-3 and has a gene expression profile consistent with the ErbB-2 genetic signature."
"We evaluated the effects of the epidermal growth factor receptor (EGFR)/HER2 inhibitor,...
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