Allograft Vasculopathy

Research data from Mayo Clinic, Medical Department update understanding of allograft vasculopathy

Published in Surgery Litigation and Law Weekly, November 9th, 2007

According to recent research from the United States, " Metabolic syndrome and elevation of inflammatory markers is common in transplant recipients. We investigated the role of insulin resistance and C-reactive protein (CRP) in predicting development of angiographic cardiac allograft vasculopathy (CAV)."

"CRP and lipid profile were measured in 114 cardiac transplant recipients at 4.7 +/- 3.1 years post-transplant. A triglyceride/high-density lipoprotein cholesterol (TG/HDL) ratio of >= 3 was considered a marker of insulin resistance. Ninety-seven patients (mean age +/- SD: 48.2 +/- 16.7 years) subsequently underwent routine coronary angiography at 8.6 +/- 3.2 years...

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Source: Surgery Litigation and Law Weekly (2007-11-09)

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