Gene Therapy

Reports from University Hospital, Division of Thoracic Surgery highlight recent research in gene therapy

Published in Surgery Litigation and Law Weekly, May 2nd, 2008

Fresh data on gene therapy are presented in the report 'PTEN expression is a strong predictor of survival in mesothelioma patients.' According to a study from Zurich, Switzerland, "Malignant pleural mesothelioma (MPM) is a highly aggressive tumor with poor prognosis and limited response to therapy. MPM is characterised by complex chromosomal aberrations, including chromosome 10 losses."

"The tumor suppressor gene phosphatase and tensin homologue deleted from chromosome 10 (PTEN) located on chromosome 10q23 plays an important role in different cancer, but its relevance for MPM is unclear. In the present tissue microarray-based study, 341 MPM were studied for PTEN...

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Source: Surgery Litigation and Law Weekly (2008-05-02)

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