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Schwannoma

Data on schwannoma detailed by researchers at University Medical Center, Department of Neurosurgery

Published in Surgery Litigation and Law Weekly, May 30th, 2008

Investigators publish new data in the report 'Overexpression of CXCL16 and its receptor CXCR6/Bonzo promotes growth of human schwannomas.' According to a study from Kiel, Germany, "Chemokines and their receptors play a decisive role in tumor progression and metastasis. Here, we describe the expression of the CXCL16-CXCR6-system in human schwannomas of different localization and in malignant peripheral nerve sheath tumors."

"The transmembrane chemokine CXCL16 and its receptor CXCR6/Bonzo were overexpressed on the mRNA and protein levels in all tumor samples investigated as compared with normal peripheral or 8th cranial nerve tissues. Chromogenic immunostaining and...

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