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Diabetes

Scientists at University of Wuerzburg detail research in diabetes

Published in Surgery Litigation and Law Weekly, May 30th, 2008

According to recent research from Wurzburg, Germany, "Adult pig islet isolation has greatly improved in the past few years. Islet grafts may now be tested in large animals."

"Continuous Glucose Monitoring System (CGMS) was applied to diabetic Goettingen Minipigs (GMP) to improve the management of hyperglycemia and hypoglycemia and their welfare before transplantation. GMP (25-35 kg) received a minipig diet once daily. Diabetes was induced by streptozotocin (STZ; 150 mg/kg intravenous [IV]; n = 5) or by surgical pancreatectomy (PGMP; n = 3). Interstitial glucose concentration (IGC) was monitored continuously with an implanted sensor; CGMS was calibrated using...

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