Abdominal Aortic Aneurysm

Study data from University of Copenhagen update understanding of abdominal aortic aneurysm

Published in Surgery Litigation and Law Weekly, July 18th, 2008

"Surgery for abdominal aortic aneurysm is associated with elevated oxidative stress. As an antioxidant in animal and human studies, melatonin has the potential of ameliorating some of this oxidative stress, but melatonin has never been administered to adults during surgery for the purpose of reducing oxidative damage," scientists in Hellerup, Denmark report.

"The aim of this pilot study was to evaluate the safety of various doses of melatonin administered during or after surgery and to monitor the changes in biomarkers of oxidative stress and inflammation during the pre-, intra-, and postoperative period. Six patients undergoing aortic surgery received 10 (n = 2), 30 (n...

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Source: Surgery Litigation and Law Weekly (2008-07-18)

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