Diabetes

Reports from Karolinska University describe recent advances in diabetes

Published in Surgery Litigation and Law Weekly, August 1st, 2008

"The ICAM-I gene is a strong positional and biological candidate for susceptibility to the development of TID and DN. We have recently demonstrated that SNP rs5498( E469K) confers susceptibility to the development of TID and might be associated with DN in Swedish Caucasians," scientists in Stockholm, Sweden report.

"The present study aimed to further evaluate the association between the ICAM-I genetic polymorphisms and DN. Two common non-synonymous SNPs, including rs5498( E469K) and rs1799969( R241G), in the ICAM-I gene were genotyped in 662 ( 312 female/350 male) TID patients with DN and 620 ( 369/251) without DN. All patients were selected from the GoKinD study....

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Source: Surgery Litigation and Law Weekly (2008-08-01)

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