Sclerosis

New sclerosis research from University of Navarra described

Published in Surgery Litigation and Law Weekly, September 5th, 2008

According to a study from Pio, Spain, "Human leukocyte antigen DR2 (HLA-DR2) is a well-established genetic risk factor for multiple sclerosis (MS). However, it is still unknown whether this factor is associated with a specific disease phenotype, and in particular, to a regional distribution of white matter (WM) lesion phenotype on magnetic resonance imaging (MRI)."

"On a voxel-by-voxel basis, we analyzed the T1 and T2 MRI-derived lesion maps of 50 patients with MS in order to determine the possible influence of HLA-DR2 genotype on the tesional. MRI pattern at early stages of the disease. HLA-DR2 was present in 15 (30%) patients of our cohort. They displayed similar WM...

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Source: Surgery Litigation and Law Weekly (2008-09-05)

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