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Gastric Cancer

New gastric cancer study findings recently were published by S. Akamoto and co-researchers

Published in Surgery Litigation and Law Weekly, January 9th, 2009

"Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are reported to be a major determiuant of variations in the sensitivity for fluoropyrimidines in gastric cancer. The aim of this study was to investigate whether there is a discrepancy in the TS and DPD expression depending on measuring method," scientists in Shizuoka, Japan report.

"The protein levels and mRNA level of TS and DPD were estimated in primary gastric cancer tissue specimens after a non-curative resection. The protein levels were determined by ELISA from frozen tissue specimens. The gene expressions were measured using real-time reverse transcriptional polymerase chain reaction (RT-PCR)....

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