Gastric Cancer

Studies from M.G. Choi et al further understanding of gastric cancer

Published in Surgery Litigation and Law Weekly, June 5th, 2009

"p12(DOC-1) is a well-known growth suppressor; however, its role in gastric carcinogenesis is still unclear. We investigated the expression of p12(DOC-1) in gastric cancer tissues and its possible correlation with p53 expression, and determined its clinical significance," scientists in Seoul, South Korea report.

"Immunohistochemical staining using the tissue array method was performed on 180 human gastric carcinomas. The clinicopathological features and prognostic significance were analyzed. Of the 180 tissue samples, p53 expression was positive in 85 (47.2%) and p12(DOC-1) expression was negative in 140 (77.8%). The negative expression of p12(DOC-1) was significantly...

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Source: Surgery Litigation and Law Weekly (2009-06-05)

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